I am a D&D5e player that is starting to branch out to other games. It was nice to find that VtM is starting a new edition, as I was looking for a jumping on point myself. The story is very interesting, however I had to improvise a few changes to make the characters more personally involved in the story. Spoilers ahead For instance, I made Webber secretly hire the "monster hunters" with AR-15s as he was looking to get out of involvement with the kindred. Additionally the flashback section needed to be removed entirely as it completely disregards player autonomy. So I had Sam reveal the necessary information from the flashback to them as they didn't remember their first few foggy days as vampires. It was also important to give the scapegoat/red herring character more of a backstory and reason to be hated by the town. In the end it felt like it needed a lot of tweaking but was still a solid premise. Guess I can't complain too much since it was free.
Mechanically speaking I can't compare it to older editions since I haven't played them. But I will say I enjoyed the controversial hunger dice very much as a GM and it added a lot of excitement to simple tests. Everything else was laid out in plain English and easy to understand and use.